joining-region gene segment - traducción al ruso
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joining-region gene segment - traducción al ruso

THE PROCESS IN WHICH IMMUNE RECEPTOR V, D, AND J, OR V AND J GENE SEGMENTS, DEPENDING ON THE SPECIFIC RECEPTOR, ARE RECOMBINED WITHIN A SINGLE LOCUS UTILIZING THE CONSERVED HEPTAMER AND NONOMER RECOMBINATION SIGNAL SEQUENCES (RSS).
VDJ recombination; Antibody gene rearrangement; VDJ recombinase; V(D)J recombinase; Antibody gene recombination; Gene arrangement; Gene re-arrangement; V-J joining; VJ recombinase; Combinatorial diversification; 12/23 rule; Somatic recombination model; Gene rearrangement; Immunogobulin gene; J gene segment; D gene segment; D segment; J segment; J region; Joining gene segment; Diversity gene segment; Vdj recombinase
  • Simplistic overview of V(D)J recombination of immunoglobulin heavy chains

joining-region gene segment      

общая лексика

J-сегмент гена (иммуноглобулина)

line segment         
PART OF A LINE THAT IS BOUNDED BY TWO DISTINCT END POINTS; LINE WITH TWO ENDPOINTS
Straight line segment; Line Segment; Line Segment (geometry); Closed line segment; Line segments; Open line segment; Half-open line segment; Line-segment; Straight line between two points; Directed line segment

общая лексика

отрезок прямой

сегмент

геометрия

отрезок

overlapping gene         
  • The [[RNA silencing suppressor p19]] from [[tomato bushy stunt virus]], a protein encoded by an overprinted gene. The protein specifically binds [[siRNA]]s produced as part of the plant's [[RNA silencing]] defense against viruses.<ref name="ye_2003" />
  • s2cid=4206886}}</ref>
  • s2cid=4355527}}</ref>
  • A [[cladogram]] indicating the likely evolutionary trajectory of the gene-dense pX region in [[human T-lymphotropic virus 1]] (HTLV1), a [[deltaretrovirus]] associated with blood cancers. This region contains numerous overlapping genes, several of which likely originated ''de novo'' through overprinting.<ref name="pavesi_2013" />
GENE WHOSE SEQUENCE PARTIALLY OVERLAPS THE READING FRAME OF ANOTHER GENE
Overlapping genes; Gene overlap; Overlapped gene; Overprinted gene; Overprinting (genetics)

общая лексика

перекрывающийся (с другими последовательностями ДНК) ген

Definición

Fc-фрагмент
часть молекулы иммуноглобулина, отщепляемая с помощью папаина и состоящая из двух С-концевых участков тяжелых цепей; не взаимодействует с антигеном; с Fc-фрагментом связаны способности иммуноглобулина фиксироваться на клетках, связывать комплемент, участвовать в реакции пассивной кожной анафилаксии.

Wikipedia

V(D)J recombination

V(D)J recombination is the mechanism of somatic recombination that occurs only in developing lymphocytes during the early stages of T and B cell maturation. It results in the highly diverse repertoire of antibodies/immunoglobulins and T cell receptors (TCRs) found in B cells and T cells, respectively. The process is a defining feature of the adaptive immune system.

V(D)J recombination in mammals occurs in the primary lymphoid organs (bone marrow for B cells and thymus for T cells) and in a nearly random fashion rearranges variable (V), joining (J), and in some cases, diversity (D) gene segments. The process ultimately results in novel amino acid sequences in the antigen-binding regions of immunoglobulins and TCRs that allow for the recognition of antigens from nearly all pathogens including bacteria, viruses, parasites, and worms as well as "altered self cells" as seen in cancer. The recognition can also be allergic in nature (e.g. to pollen or other allergens) or may match host tissues and lead to autoimmunity.

In 1987, Susumu Tonegawa was awarded the Nobel Prize in Physiology or Medicine "for his discovery of the genetic principle for generation of antibody diversity".

¿Cómo se dice joining-region gene segment en Ruso? Traducción de &#39joining-region gene segment&#39